ODCs

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1 OMIM reference -
1 associated gene
4 signs/symptoms

PROTEIN INTERACTIONS: 1

1 OMIM reference -
2 associated genes
No signs/symptoms info

Mendelian susceptibility to mycobacterial diseases due to partial IRF8 deficiency

Fibrosarcoma

IRF8	(UniProt - OMIM)		ETV6	(UniProt - OMIM)
			NTRK3	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	IRF8	(0.72)	ETV6

Citations in the biomedical literature:

Mendelian susceptibility to mycobacterial diseases due to partial IRF8 deficiency		Fibrosarcoma
	Synonym(s): - MSMD due to partial IRF8 deficiency - MSMD due to partial interferon regulatory factor 8 deficiency - Mendelian susceptibility to mycobacterial diseases due to partial interferon regulatory factor 8 deficiency		Synonym(s): (no synonyms)

	Classification (Orphanet): - Rare genetic disease - Rare immune disease		Classification (Orphanet): - Rare bone disease - Rare oncologic disease

	Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -		Classification (ICD10): (no data available)

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: neonatal/infancy Average age of death: normal Type of inheritance: autosomal dominant		Epidemiological data: (no data available)

	External references: 1 OMIM reference - No MeSH references		External references: 1 OMIM reference - 1 MeSH reference: D005354

Mendelian susceptibility to mycobacterial diseases due to partial IRF8 deficiency
	Very frequent - Autosomal dominant inheritance - Fever / chilling - Immunodeficiency / increased susceptibility to infections / recurrent infections - Lymphadenopathy / polyadenopathies
Fibrosarcoma
(no data available)